| 2025 | 42 | Boseong Jo, Semin Lee, Sang-Hun Kim, Ki-Jun Ryu, Kwang Dong Kim, Ji Yun Yoo, Cheol Hwangbo, and Kwon HK Syrosingopine targeting the MCT4 inhibit inflammation mediated by the immune response. Preparing for submission |
| 41 | Semin Lee, Boseong Jo, Ki Won Lee, Hyo‑Jin Kim, Ki-Jun Ryu, Hong-Yeoul Ryu, Kwang Dong Kim, Ji Yun Yoo, Cheol Hwangbo, and Kwon HK Proteomic Profiling of Proteins Enriched in Extracellular Vesicles Derived from NLRP3 Inflammasome-Activated Macrophages. Preparing for submission | |
| 40 | Dahee Choi, Ann-Yae Na, Seok-Won Jeoung, Yun-Hee Choi, Nayoon Park, Hyun-Sun Park, Hyun-Shik Lee, Kwon HK, Dong-Hyung Cho, Dong Hyun Kim, and Hong-Yeoul Ryu Histon H3 lysine 9 tri-methylation is associated with pterygium. Revision in BMC Ophthalmology | |
| 39 | Ryu JH, Song MS, Nyiramana MM, Prayoga AH, Cao DL, Lee GW, Kwon HK, Kang D. Sea hare hydrolysate reduces PD-L1 levels in cancer cells and mitigates rheumatoid arthritis in a collagen-induced arthritis mouse model. Food Science & Nutrition. 2025; 13:e4644. doi: 10.1002/fsn3.4644 | |
| 2024 | 38 | Ryu KJ, Lee KW, Park SH, Kim T, Hong KS, Kim H, Kim M, Ok DW, Kwon GNB, Park YJ, Kwon HK, Hwangbo C, Kim KD, Lee JE, Yoo J. Chaperone-mediated autophagy modulates Snail protein stability: Implications for breast cancer metastasis. Molecular Cancer. 2024 Oct 11;23(1):227. doi: 10.1186/s12943-024-02138-0. PMID: 39390584 |
| 37 | Kim SG, Duong TV, Lee S, Ryu K, Kwon HK, Park HS. Synergistic inhibition of colorectal cancer cells by autocrine motility factor peptide and glycyrrhetinic acid. Discovery Medicine. 2024 Oct;36(189):2063-2070. doi: 10.24976/Discov.Med.202436189.190. PMID: 39463226. | |
| 36 | Min WH, Ko CY, Kim H, Kwon HK, Jang HJ, Bach TT, Han LN, Lee JH, Kim HJ, Hwangbo C. Anti‑inflammatory effects of methanol extract from Peperomia dindygulensis Miq. mediated by HO‑1 in LPS‑induced RAW 264.7 cells. Experimental and Therapeutic Medicine. 2024 Jun 14;28(2):317. doi: 10.3892/etm.2024.12606. PMID: 38939180. | |
| 2023 | 35 | Kwon HK, Yu KE, Cahill SV, Alder KD, Dussik CM, Jeong J, Back J, Lee FY. Parathyroid hormone therapy improves bone healing in MRSA-infected open fracture diabetic models. Frontiers in Cellular and Infection Microbiology. 2023 Sep 27;13:1230568. doi: 10.3389/fcimb.2023.1230568. PMID: 37829606 |
| 34 | Agidigbi TS, Kwon HK, Knight JR, Zhao D, Lee FY, Oh I. Transcriptomic identification of genes expressed in invasive S. aureus diabetic foot ulcer infection. Frontiers in Cellular and Infection Microbiology. 2023 Jun 26;13:1198115. doi: 10.3389/fcimb.2023.1198115. PMID: 37434783 | |
| 33 | Kwon HK, Yu KE, Lee FY. Construction and evaluation of a septic arthritis murine model. Lab Animal (NY). 2023 Jan;52(1):11-26. doi: 10.1038/s41684-022-01089-7. Epub 2022 Dec 23. PMID: 36564668. (Cover illustration) | |
| 2022 | 32 | Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ. VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 2022 Nov 30. doi: 10.1165/rcmb.2022-0219OC. Epub ahead of print. PMID: 36450109. |
| 31 | Kwon HK, Yu KE, Cahill SV, Alder KD, Dussik CM, Kim SH, Sharma L, Back J, Oh I, Lee FY. Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis. EMBO Molecular Medicine. 2022 Dec 7;14(12):e15284. doi: 10.15252/emmm.202115284. Epub 2022 Nov 10. PMID: 36354099. | |
| 30 | Kwon HK, Dussik CM, Kim SH, Kyriakides TR, Oh I, Lee FY. Treating 'Septic' With Enhanced Antibiotics and 'Arthritis' by Mitigation of Excessive Inflammation. Frontiers in Cellular and Infection Microbiology. 2022 Jun 9;12:897291. doi: 10.3389/fcimb.2022.897291. PMID: 35755835 | |
| 29 | Yu KE, Kwon HK, Dussik CM, Cahill SV, Back J, Alder KD, Lee FY. Enhancement of Impaired MRSA-Infected Fracture Healing by Combinatorial Antibiotics and Modulation of Sustained Inflammation. Journal of Bone and Mineral Research. 2022 May 26;. doi: 10.1002/jbmr.4570. PMID: 35616626. | |
| 2021 | 28 | Back J, Nguyen MN, Li L, Lee S, Lee I, Chen F, Gillinov L, Chung YH, Alder KD, Kwon HK, Yu KE, Dussik CM, Hao Z, Flores MJ, Kim Y, Ibe IK, Munger AM, Seo SW, Lee FY. Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction. Bone Research. 2021 Sep 29;9(1):43. doi: 10.1038/s41413-021-00158-w. PMID: 34588427. |
| 27 | Kwon HK, Lee I, Yu KE, Cahill SV, Alder KD, Lee S, Dussik CM, Back J, Choi J, Song L, Kyriakides TR, Lee FY. Dual therapeutic targeting of intra-articular inflammation and intracellular bacteria enhances chon-droprotection in septic arthritis. Science Advances. 2021 Jun;7(26). doi: 10.1126/sciadv.abf2665. Print 2021 Jun. PMID: 34172438. (Research Highlight in Nature Reviews Rheumatology; 2021 Sep;17. PMID: 34316064) | |
| 26 | Loye AM, Kwon HK, Dellal D, Ojeda R, Lee S, Davis R, Nagle N, Doukas PG, Schroers J, Lee FY, Kyriakides TR. Biocompatibility of platinum-based bulk metallic glass in orthopedic applications. Biomedical materials. 2021 May 7;16(4). doi: 10.1088/1748-605X/abf981. PMID: 33873168. | |
| 25 | Cahill SV, Kwon HK, Back J, Lee I, Lee S, Alder KD, Hao Z, Yu KE, Dussik CM, Kyriakides TR, Lee FY. Locally delivered adjuvant biofilm-penetrating antibiotics rescue impaired endochondral fracture healing caused by MRSA infection. Journal of orthopaedic research. 2021 Feb;39(2):402-414. doi: 10.1002/jor.24965. Epub 2021 Jan 13. PMID: 33336805. | |
| 24 | Hao Z, Li J, Li B, Alder KD, Cahill SV, Munger AM, Lee I, Kwon HK, Back J, Xu S, Kang MJ, Lee FY. Smoking Alters Inflammation and Skeletal Stem and Progenitor Cell Activity During Fracture Healing in Different Murine Strains. Journal of Bone and Mineral Research. 2021 Jan;36(1):186-198. doi: 10.1002/jbmr.4175. Epub 2020 Sep 24. PMID: 32866293. | |
| 2020 | 23 | Yu KE, Alder KD, Morris MT, Munger AM, Lee I, Cahill SV, Kwon HK, Back J, Lee FY. Re-appraising the potential of naringin for natural, novel orthopedic biotherapies. Therapeutic advances in musculoskeletal disease. 2020;12:1759720X20966135. doi: 10.1177/1759720X20966135. eCollection 2020. Review. PMID: 33343723. |
| 22 | Alder KD, Lee I, Munger AM, Kwon HK, Morris MT, Cahill SV, Back J, Yu KE, Lee FY. Intracellular Staphylococcus aureus in bone and joint infections: A mechanism of disease recurrence, inflammation, and bone and cartilage destruction. Bone. 2020 Dec;141:115568. doi: 10.1016/j.bone.2020.115568. Epub 2020 Jul 31. Review. PMID: 32745687. | |
| 21 | Alder KD, White AH, Chung YH, Lee I, Back J, Kwon HK, Cahill SV, Hao Z, Li L, Chen F, Lee S, Riedel MD, Lee FY. Systemic Parathyroid Hormone Enhances Fracture Healing in Multiple Murine Models of Type 2 Diabetes Mellitus. JBMR Plus. 2020 May;4(5):e10359. doi: 10.1002/jbm4.10359. eCollection 2020 May. PMID: 32382692. | |
| 20 | Yu K, Song L, Kang HP, Kwon HK, Back J, Lee FY. Recalcitrant methicillin-resistant Staphylococcus aureus infection of bone cells: Intracellular penetration and control strategies. Bone and Joint Research. 2020 Feb;9(2):49-59. doi: 10.1302/2046-3758.92.BJR-2019-0131.R1. eCollection 2020 Feb. PMID: 32435455. | |
| 19 | Achek A, Kwon HK, Patra MC, Shah M, Hong R, Lee WH, Baek WY, Choi YS, Kim GY, Pham TLH, Suh CH, Kim W, Hahm DH, Choi S. A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models. EBioMedicine. 2020 Feb;52:102645. doi: 10.1016/j.ebiom.2020.102645. Epub 2020 Feb 1. PMID: 32014819. | |
| 2019 | 18 | Achek A, Shah M, Seo JY, Kwon HK, Gui X, Shin HJ, Cho EY, Lee BS, Kim DJ, Lee SH, Yoo TH, Kim MS, Choi S. Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model. Journal of Medicinal Chemistry. 2019 Jul 25;62(14):6495-6511. doi: 10.1021/acs.jmedchem.9b00061. Epub 2019 Jul 8. PMID: 31283217. |
| 17 | Kwon HK, Patra MC, Shin HJ, Gui X, Achek A, Panneerselvam S, Kim DJ, Song SJ, Hong R, Kim KS, Kim YG, Lee FY, Hahm DH, Lee SH, Choi S. A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice. Experimental and Molecular Medicine. 2019 Apr 26;51(4):1-19. doi: 10.1038/s12276-019-02440. PMID: 31028244. | |
| 2018 | 16 | Patra MC, Kwon HK, Batool M, Choi S. Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer. Frontiers in Immunology. 2018;9:489. doi: 10.3389/fimmu.2018.00489. eCollection 2018. PMID: 29593733. |
| 15 | Lee JH, Kwon HK, Shin HJ, Nam GH, Kim JH, Choi S. Quasi-Stem Cells Derived from Human Somatic Cells by Chemically Modified Carbon Nanotubes. ACS Applied Materials and Interfaces. 2018 Mar 14;10(10):8417-8425. doi: 10.1021/acsami.7b12914. Epub 2018 Mar 2. PMID: 29286621. | |
| 2017 | 14 | Kim DJ, Kang JM, Park SH, Kwon HK, Song SJ, Moon H, Kim SM, Seo JW, Lee YH, Kim YG, Moon JY, Lee SY, Son Y, Lee SH. Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β1 and Shh Signalling. Scientific Reports. 2017 Dec 1;7(1):16782. doi: 10.1038/s41598-017-16977-z. PMID: 29196746. |
| 13 | Durai P, Shin HJ, Achek A, Kwon HK, Govindaraj RG, Panneerselvam S, Yesudhas D, Choi J, No KT, Choi S. Toll-like receptor 2 antagonists identified through virtual screening and experimental validation. FEBS Journal. 2017 Jul;284(14):2264-2283. doi: 10.1111/febs.14124. Epub 2017 Jul 2. PMID: 28570013. | |
| 12 | Park S, Shin HJ, Shah M, Cho HY, Anwar MA, Achek A, Kwon HK, Lee B, Yoo TH, Choi S. TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation. Biomaterials. 2017 May;126:49-60. doi: 10.1016/j.biomaterials.2017.02.023. Epub 2017 Feb 20. PMID: 28254693. | |
| 2016 | 11 | Panneerselvam S, Durai P, Yesudhas D, Achek A, Kwon HK, Choi S. Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study. RSC advances. 2016 October 17; 6:100804-100819. doi: 10.1039/C6RA16343B. |
| 10 | Shin HJ, Kwon HK, Lee JH, Anwar MA, Choi S. Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells. Scientific Reports. 2016 Sep 26;6:34064. doi: 10.1038/srep34064. PMID: 27666530. | |
| 2015 | 9 | Shin HJ, Kwon HK, Lee JH, Gui X, Achek A, Kim JH, Choi S. Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53. Scientific Reports. 2015 Nov 2;5:15798. doi: 10.1038/srep15798. PMID: 26522181. |
| 8 | Kwon HK, Lee JH, Shin HJ, Kim JH, Choi S. Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death. Scientific Reports. 2015 Oct 22;5:15623. doi: 10.1038/srep15623. PMID: 26490051. | |
| 7 | Kwon JW, Kwon HK, Shin HJ, Choi YM, Anwar MA, Choi S. Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB. Scientific Reports. 2015 Sep 28;5:14470. doi: 10.1038/srep14470. PMID: 26412238. | |
| 6 | Kwon HK, Shin HJ, Lee JH, Park SH, Kwon MC, Panneerselvam S, Lee CG, Kim SG, Kim JH, Choi S. Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells. Toxicological Sciences. 2015 Nov;148(1):204-19. doi: 10.1093/toxsci/kfv182. Epub 2015 Aug 10. PMID: 26259609. (Cover illustration) | |
| 5 | Choi YM, Kim HK, Shim W, Anwar MA, Kwon JW, Kwon HK, Kim HJ, Jeong H, Kim HM, Hwang D, Kim HS, Choi S. Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation. PLoS One. 2015;10(8):e0135083. doi: 10.1371/journal.pone.0135083. eCollection 2015. PMID: 26247588. | |
| 2014 | 4 | Lee CG, Kim JG, Kim HJ, Kwon HK, Cho IJ, Choi DW, Lee WH, Kim WD, Hwang SJ, Choi S, Kim SG. Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury. Kidney International. 2014 Nov;86(5):943-53. doi: 10.1038/ki.2014.117. Epub 2014 Apr 23. PMID: 24759152. |
| 2012 | 3 | Park EJ, Kwon HK, Choi YM, Shin HJ, Choi S. Doxorubicin induces cytotoxicity through upregulation of pERK-dependent ATF3. PLoS One. 2012;7(9):e44990. doi: 10.1371/journal.pone.0044990. Epub 2012 Sep 13. PMID: 23028726. |
| 2011 | 2 | Park EJ, Kim SA, Choi YM, Kwon HK, Shim W, Lee G, Choi S. Capric acid inhibits NO production and STAT3 activation during LPS-induced osteoclastogenesis. PLoS One. 2011;6(11):e27739. doi: 10.1371/journal.pone.0027739. Epub 2011 Nov 16. PMID: 22110749. |
| 2010 | 1 | Kim EY, Shin HY, Kim JY, Kim DG, Choi YM, Kwon HK, Rhee DK, Kim YS, Choi S. ATF3 plays a key role in Kdo2-lipid A-induced TLR4-dependent gene expression via NF-κB activation. PLoS One. 2010 Dec 2;5(12):e14181. doi: 10.1371/journal.pone.0014181. PMID: 21152039. |