수의과대학 수의과대학

교수님소개

학력 사항

• 충남대학교 수의과대학 (1987, 수의학사) : Chungnam National University College of Veterinary Medicine (1987, Bachelor)
• 충남대학교 대학원 수의학과 (1989, 수의학석사): Chungnam National University, College of Veterinary Medicine (1989, Master degree)
• 서울대학교 대학원 수의학과 (1998, 수의학박사): Seoul National University, College of Veterinary Medicine (1998, Ph.D)

경력 사항

• 1998. 04. - 1999. 0.1 연수 연구원 (생명공학연구소, 분자생물학) : Research Institute (Research Institute of Biotechnology, Molecular Biology).
• 1999. 02. - 2004. 02. 연수 연구원 (USDA-ARS) : Post-doc. (USDA-ARS, USA).
• 2008. 12. - 2013. 08. 세계수준의 연구중심대학(WCU) 육성사업 단장: Head, World-Class Research University (WCU) Promotion Project.
• 2012. 03. - 2019: 경상남도 가축방역협의회 위원: Council Member at Gyeongsangnam-do Livestock Prevention.
• 2014. 03. - 2015. 12 동물의학연구소 소장 : Director, Institute of Animal Medicine.
• 2016. 01. - 2017. 12. 경상대학교 수의과대학 학장: Dean, College of Veterinary Medicine, Gyeongsang National University.
• 2017. 05. - 현재: 대한수의학회지 부편집위원 : Associate Editor, Journal of Veterinary Research.

연구내용

• 인수공통전염병으로 사회적 관심이 많은 조류인플루엔자 바이러스에 대한 검사 등 ( Diagnosis of avian influenza virus, which is one of great infectious viruses in poultry).
• 조류(닭과 오리)질병에 대한 면역학 (특히, Th17)에 대한 연구 (Studies on immunology (especially Th17) against bird (chicken and duck) diseases).
• 닭의 콕시듐(Eimeria)의 억제하기 위한 천연물질을 이용, 백신개발 등 (Use of natural substances to inhibit coccidiosis (Eimeria) in chickens and vaccine development, etc.).
• 닭에서 염증성 반능을 일으키는 면역반능에 대한 연구를 수행하고 있다. 또한 오리에서 염증성 반응을 심각하게 유발하는 리메렐라에 대한 연구를 수행하고 있다 (We are conducting research on immune reactions that cause inflammatory reactions in chickens. He is also conducting research on duck Riemerella infection, which causes severe inflammatory reactions in ducks.).
  

주요 연구업적(Publications)

• Fernandez-Colorado CP, Cammayo PLT, Flores RA, Nguyen BT, Kim WH, Kim S, Lillehoj HS, Min W. Anti-inflammatory activity of diindolylmethane alleviates Riemerella anatipestifer?infection in ducks. PLoS One. 2020 Nov 11;15(11):e0242198.
• Cammayo PLT, Fernandez-Colorado CP, Flores RA, Roy A, Kim S, Lillehoj HS, Kim WH, Min W. IL-17A treatment influences murine susceptibility to experimental Riemerella anatipestifer infection. Dev Comp Immunol. 2020 May;106:103633.
• Kim WH, Lillehoj HS, Min W. Indole Treatment Alleviates Intestinal Tissue Damage Induced by Chicken Coccidiosis Through Activation of the Aryl Hydrocarbon Receptor. Front Immunol. 2019 Mar 26;10:560.
• Fernandez CP, Afrin F, Flores RA, Kim WH, Jeong J, Kim S, Lillehoj HS, Min W. Identification of duck IL-4 and its inhibitory effect on IL-17A expression in R. anatipestifer-stimulated splenic lymphocytes. Mol Immunol. 2018 Mar;95:20-29.
• Afrin F, Fernandez CP, Flores RA, Kim WH, Jeong J, Chang HH, Kim S, Lillehoj HS, Min W. Downregulation of common cytokine receptor γ chain inhibits inflammatory responses in macrophages stimulated with Riemerella anatipestifer. Dev Comp Immunol. 2018 Apr;81:225-234.
• Fernandez CP, Afrin F, Flores RA, Kim WH, Jeong J, Kim S, Chang HH, Lillehoj HS, Min W. Downregulation of inflammatory cytokines by berberine attenuates Riemerella anatipestifer infection in ducks. Dev Comp Immunol. 2017 Dec;77:121-127.
• Kim WH, Lillehoj HS, Min W. Evaluation of the Immunomodulatory Activity of the Chicken NK-Lysin-Derived Peptide cNK-2. Sci Rep. 2017 Mar 23;7:45099.
• Kim WH, Lillehoj HS, Lim Y, Min W, Sullivan YB, Kakach L, LaBresh JW. Development and characterization of mouse monoclonal antibodies reactive with chicken CXCLi2. Dev Comp Immunol. 2017 Jul;72:30-36.
• Fernandez CP, Kim WH, Diaz JA, Jeong J, Afrin F, Kim S, Jang HK, Lee BH, Yim D, Lillehoj HS, Min W. Upregulation of duck interleukin-17A during Riemerella anatipestifer infection. Dev Comp Immunol. 2016 Oct;63:36-46.
• Diaz JA, Kim WH, Fernandez CP, Jeong J, Afrin F, Lillehoj HS, Kim S, Kim S, Dalloul RA, Min W. Identification and expression analysis of duck interleukin-17D in Riemerella anatipestifer infection. Dev Comp Immunol. 2016 Aug;61:190-7.
• Kim WH, Fernandez CP, Diaz JA, Jeong J, Kim S, Lillehoj HS, Chang HH, Min W. Molecular cloning, characterization and mRNA expression of duck interleukin-17F. Vet Immunol Immunopathol. 2015 Apr 15;164(3-4):194-200.
• Jeong J, Kim WH, Yeo J, Fernandez CP, Kim S, Lee YJ, Lillehoj HS, Min W. Identification of alternatively spliced isoforms of interleukin-2/15 receptor β chain in ducks. Vet Immunol Immunopathol. 2014 Dec 15;162(3-4):154-161.
• Jeong J, Kim WH, Fernandez CP, Kim S, Kim YH, Jang HK, Lillehoj HS, Woo HJ, Min W. Different strategies for producing naturally soluble form of common cytokine receptor γ chain. Dev Comp Immunol. 2015 Jan;48(1):13-21.
• Lee SH, Lillehoj HS, Jeong MS, Del Cacho E, Kim JB, Kim HR, Min W, Jeoung HY, An DJ. Development and characterization of mouse monoclonal antibodies reactive with chicken IL-1β. Poult Sci. 2014 Sep;93(9):2193-2198.
• Kim WH, Jeong J, Park AR, Yim D, Kim S, Chang HH, Yang SH, Kim DH, Lillehoj HS, Min W. Downregulation of chicken interleukin-17 receptor A during Eimeria infection. Infect Immun. 2014 Sep;82(9):3845-3854.
• Lee SH, Lillehoj HS, Jeong M, Del Cacho E, Min W, Sullivan YB, Kakach L, Labresh JW, Kim HR, Chune HK. Development and characterization of mouse monoclonal antibodies reactive with chicken TL1A. Vet Immunol Immunopathol. 2014 May 15;159(1-2):103-9.
• Kim DK, Lillehoj HS, Lee SH, Jang SI, Park MS, Min W, Lillehoj EP, Bravo D. Immune effects of dietary anethole on Eimeria acervulina infection. Poult Sci. 2013 Oct;92(10):2625-34.
• Min W, Kim WH, Lillehoj EP, Lillehoj HS. Recent progress in host immunity to avian coccidiosis: IL-17 family cytokines as sentinels of the intestinal mucosa. Dev Comp Immunol. 2013 Nov;41(3):418-28.
• Lee SH, Lillehoj HS, Jang SI, Lillehoj EP, Min W, Bravo DM. Dietary supplementation of young broiler chickens with Capsicum and turmeric oleoresins increases resistance to necrotic enteritis. Br J Nutr. 2013 Sep 14;110(5):840-7.
• Kim WH, Jeong J, Park AR, Yim D, Kim YH, Kim KD, Chang HH, Lillehoj HS, Lee BH, Min W. Chicken IL-17F: identification and comparative expression analysis in Eimeria-infected chickens. Dev Comp Immunol. 2012 Nov;38(3):401-9.
• Jeong J, Kim WH, Yoo J, Lee C, Kim S, Cho JH, Jang HK, Kim DW, Lillehoj HS, Min W. Identification and comparative expression analysis of interleukin 2/15 receptor β chain in chickens infected with E. tenella. PLoS One. 2012;7(5):e37704.
• Kim DK, Lillehoj H, Min W, Kim CH, Park MS, Hong YH, Lillehoj EP. Comparative microarray analysis of intestinal lymphocytes following Eimeria acervulina, E. maxima, or E. tenella infection in the chicken. PLoS One. 2011;6(11):e27712.
• Yoo J, Kang SH, Jeong J, Kim WH, Kim S, Lillehoj HS, Min W. Effects of simple and disposable chicken cages for experimental Eimeria infections. Korean J Parasitol. 2011 Sep;49(3):299-302.
• Jang SI, Lillehoj HS, Lee SH, Kim DK, Pages M, Hong YH, Min W, Lillehoj EP. Distinct immunoregulatory properties of macrophage migration inhibitory factors encoded by Eimeria parasites and their chicken host. Vaccine. 2011 Nov 8;29(48):8998-9004.
• Lee SH, Lillehoj HS, Jang SI, Baldwin C, Tompkins D, Wagner B, Parcells M, Del Cacho E, Hong YH, Min W, Lillehoj EP. Development and characterization of mouse monoclonal antibodies reactive with chicken interleukin-2 receptor αlpha chain (CD25). Vet Immunol Immunopathol. 2011 Dec 15;144(3-4):396-404.
• Lee SH, Lillehoj HS, Park MS, Baldwin C, Tompkins D, Wagner B, Del Cacho E, Babu U, Min Wongi (2011). Development and characterization of mouse monoclonal antibodies reactive with chicken CD80. Comp Immunol Microbiol Infect Dis. May;34(3):273-279.
• Yim D, Kang SS, Lillehoj HS, Min Wongi (2011). A simple and efficient method for isolation of a single Eimeria oocyst from poultry litter using a micromanipulator. Res Vet Sci. 2011 Apr;90(2):260-261.
• Jipseol Jeong, Changhwan Lee, Jeongmi Yoo, Phil-Ok Koh, Yong-Hwan Kim, Hong H. Chang, Nong-Hoon Choe, Hyun S. Lillehoj, Wongi Min (2011). Molecular identification of duck and quail common cytokine receptor gamma chain genes. Veterinary Immunology and Immunopathology. 140, 159-165.
• Dongjean Yim, Sang S. Kang, Dong W. Kim, Sang H. Kim, Hyun S. Lillehoj, Wongi Min (2011). Protective effects of Aloe vera-based diets in Eimeria maxima-infected broiler chickens. Experimental Parasitology. 127, 322-325.
• Yeong H. Hong, Hyun S. Lillehoj., Sung Hyen Lee, Myeong-Sun Park, Wongi Min, Joanna LaBresh, Dannielle Tompkins, Cynthia Baldwin (2010). Development and characterization of mouse monoclonal antibodies specific for chicken interleukin · Veterinary Immunology and Immunopathology. 132. 144-148.
• Sung-Hyen Lee, Hyun S. Lillehoj., Seung I. Jang, Yeong-Ho Hong, Wongi Min, Erik P. Lillehoj, Robert J. Yancey, Paul Dominowski (2010). Embryo vaccination of chickens using a novel adjuvant formulation stimulates protective immunity against Eimeria maxima infection. Vaccine. 28, 7774-7778.
• Byung H. Lee, Woo H. Kim, Jipseol Jeong, Jeongmi Yoo, Yong-Kuk Kwon, Byeong Y. Jung, Jun H. Kwon, Hyun S. Lillehoj, Wongi Min (2010). Prevalence and Cross-Immunity of Eimeria Species on Korean Chicken Farms. The Journal of Veterinary Medical Science. 72(8). 985-989.
• Yoo J, Jang SI, Kim S, Cho JH, Lee HJ, Rhee MH, Lillehoj HS, Min W (2009). Molecular characterization of duck interleukin-17. Veterinary Immunology and Immunopathology. 132, 318-322.
• Gutierrez WM, Min W, Chang HH (2009). Effects of Chilled Drinking Water on Performance of Laying Hens during Constant High Ambient Temperature. Asian-Aust. J. Anim. Sci.?22, 694-699.
• Kim CH, Lillehoj HS, Bliss TW, Keeler CL Jr, Hong YH, Park DW, Yamage M, Min W, Lillehoj EP (2008). Construction and application of an avian intestinal intraepithelial lymphocyte cDNA microarray (AVIELA) for gene expression profiling during Eimeria maxima infection. Veterinary Immunology and Immunopathology. 124, 341-354.
• Eun Ah Yoo, Sung Dae Kim, Whi Min Lee, Hwa Jin Park, Sang Keun Kim, Jae Youl Cho, Wongi Min, and Man Hee Rhe (2008). Evaluation of anti-oxidant, anti-nociceptive, and anti-inflammatory activities of ethanol extracts from Aloe saponaria Haw. Phytotherapy Research. 22, 1389-1395.
• Yang Hyunho, Bae Yeongwan, Min Wongi (2008). Implantable wireless sensor network to monitor the deep body temperature of broilers. Journal of the Korea Academic-Industrial cooperation Society. 9(1), 81-86.
• Yoo J, Chang HH, Bae YH, Seong CN, Choe NH, Lillehoj HS, Park JH, Min Wongi (2008) Monoclonal antibodies reactive with chicken interleukin-17. Veterinary Immunology and Immunopathology. 121, 359-363.
• Seung I. Jang, Moo-hyung Jun, Hyun S. Lillehoj, Rami A. Dalloul, Il K. Kong, Suk Kim, Wongi Min (2007). Anticoccidial effect of green tea-based diets against Eimeria maxima. Veterinary Parasitology. 144(1-2),172-175.
• Seung-Ik Jang, Nyun-Ki Chung, Wongi Min, Myung-Jo You, Bae-Keun Park, Moo-Hyung Jun (2006). Effects of the feeds supplemented with Korean green tea and lactic acid bacteria on infection of Eimeria maxima in chickens. Journal of Veterinary Clinics. 23(3), 243-250.
• E.-S. Kim, Y. H. Hong, W. Min, H. S. Lillehoj (2006) Fine-mapping of coccidia-resistant quantitative trait loci in chickens. Poultry Science. 85(11), 2028-2030.
• Hong YH, Lillehoj HS, Dalloul RA, Min W, Miska KB, Tuo W, Lee SH, Han JY, Lillehoj EP (2006). Molecular cloning and characterization of chicken NK-lysin. Veterinary Immunology and Immunopathology. 110(3-4), Apr, 339-347.
• Wongi Min, Hyun S. Lillehoj, Christopher M. Ashwell, Curtis P. van Tassell, Rami A. Dalloul, Lakshmi K. Matukumalli, Jae Y. Han, Erik P. Lillehoj (2005). EST analysis of Eimeria-stimulated intestinal intraepithelial lymphocytes in chickens. Molecular Biotechnology. 30(2), June, 143-149.
• Xicheng Ding, Hyun S. Lillehoj, Rami A. Dalloul, Wongi Min, Takanori Sato, Atsushi Yasuda, and Erik P. Lillehoj (2005). In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis. Vaccine, 23(28), May, 3733-3740.
• Rami A. Dalloul, Hyun S. Lillehoj, Dennis M. Klinman, Xicheng Ding, Wongi Min, Robert A. Heckert, Erik P. Lillehoj (2005). In ovo administration of CpG oligodeoxynucleotides and the recombinant microneme protein MIC2 protects against Eimeria infections. Vaccine. 23(24), May, 3108-3113.
• Miska KB, Fetterer RH, Min W, Lillehoj HS (2005). Heat shock protein 90 genes of two species of poultry Eimeria: expression and evolutionary analysis. Journal of Parasitology. 91(2), Apr, 300-306.
• X.J. Yin, H.S. Lee, Y.H. Lee, Y.I. Seo, S.J. Jeon, E.G. Cho, S.G.Cho, W. Min, S.K. kang, W.S. Hwang, I.K. Kong (2005). Cats cloned from fetal and adult somatic cells by nuclear transfer. Reproduction. 129(2), February, 245-249.
• Rami A. Dalloul, Hyun S. Lillehoj, Masashi Okamura, Hang Xie, Wongi Min, Xicheng Ding, Robert A. Heckert (2004). In Vivo Effects of CpG Oligodeoxynucleotide on Eimeria Infection in Chickens. Avian Diseases. 48(4), December, 783-790.
• Wongi Min, Rami A. Dalloul, Hyun S. Lillehoj (2004). Appilcation of biotechnological tools for coccidia vaccine development. Journal of Veterinary Science. 5(4), December, 279-288. Review.
• Hyun S. Lillehoj, Wongi Min, Dalloul R. A. (2004) Recent progress on the cytokine regulation of intestinal immune responses to Eimeria. Poulry Science. 83(4), April, 611-623. Ancillary scientists symposium.
• Wongi Min, Hyun Soon Lillehoj (2004). Identification and characterization of chicken interleukin-16 cDNA. Developmental & Comparative Immunology. 28(2), February, 153-162.
• Wongi Min, Hyun S. Lillehoj, Sungwon Kim, James J. Zhu, Hunter Beard, Nadim Alkharouf, Benjamin F. Matthews (2003). Profiling local gene expression changes associated with Eimeria maxima and Eimeria acervulina using cDNA microarray. Applied Microbiology and Biotechnology. 62(4), September, 392-399.
• J.J. Zhu, H.S. Lillehoj, P.C. Allen, C.P. Van Tassell, T.S. Sonstegard, H.H. Cheng, D. Pollock, M. Sadjadi, W. Min, M.G. Emara (2003). Mapping quantitative trait loci associated with resistance to coccidiosis and growth. Poultry Science. 82(1), January, 9-16.
• Wongi Min, Hyun S. Lillehoj, Raymond Hugh Fetterer (2002). Identification of an alternatively spliced isoform of the common cytokine receptor γ chain in chickens. Biochemical and Biophysical Research Communications. 299(2), November, 321-327.
• Wongi Min, Hyun Soon Lillehoj (2002). Isolation and characterization of chicken interleukin-17 cDNA. Journal of Interferon & Cytokine Research. 22(11), November, 1123-1128.
• Wongi Min, Hyun S. Lillehoj, Guangxing Li, Eun J. Sohn, Tadashi Miyamoto (2002). Development and characterization of monoclonal antibodies to chicken interleukin-15. Veterinary Immunology and Immunopathology. 88(1-2), September, 49-56.
• Tadashi Miyamoto, Wongi Min, Hyun. S. Lillehoj (2002). Kinetics of interleukin-2 production in chickens infected with Eimeria tenella. Comparative Immunology, Microbiology & Infectious Diseases. May, 25(3), 149-158.
• Tadashi Miyamoto, Wongi Min, Hyun. S. Lillehoj (2002). Lymphocyte proliferation response during Eimeria tenella infection assessed by a new, reliable, nonradioactive colorimetric assay. Avian Diseases. January-March, 46(1), 10-16.
• Wongi Min, Hyun S. Lillehoj, Joan Burnside, Kirsten. C. Weining, Peter Staeheli, James J. Zhu (2001). Adjuvant effects of IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ, TGF-β4 and lymphotactin on DNA vaccination against Eimeria acervulina. Vaccine. October, 20(1-2), 267-274.
• Guangxing Li, Hyun S. Lillehoj, Wongi Min (2001). Production and characterization of monoclonal antibodies reactive with the chicken interleukin-15 receptor alpha chain. Veterinary Immunology and Immunopathology. October, 82(3-4), 215-227.
• Hyun Soon Lillehoj, Wongi Min, Kang Duk Choi, Uma S. Babu, Joan Burnside, Tadashi Miyamoto, Benjamin M. Rosenthal, Erik P. Lillehoj (2001). Molecular, cellular, and functional characterization of chicken cytokines homologous to mammalian IL-15 and IL-2. Veterinary Immunology and Immunopathology. October, 82(3-4), 229-244.
• Hyun S. Lillehoj, J. Zhu, Wongi Min (2001). Application of DNA marker technology and functional genomics to the development of coccidiosis control strategy. Korean J. Poult. Sci. 28(2), August, 107-123. Review.
• Tadashi Miyamoto, Hyun. S. Lillehoj, Eun J. Shon, Wongi Min (2001). Production and charaterization of monoclonal antibodies detecting chicken interleukin-2 and the development of an antigen capture enzyme-linked immunosorbert assay. Veterinary Immunology and Immunopathology. August, 80(3-4), 245-257.
• Wongi Min, Jin-Kyoo Kim, Hyun Soon Lillehoj, Eun Jung Sohn, Jae Yong Han, Ki Duk Song, Erik Peter Lillehoj (2001). Characterization of recombinant scFv antibody reactive with an apical antigen of Eimeria acervulina. Biotechnology Letters. June, 23(12), 949-955.
• Jin-Kyoo Kim, Wongi Min, Hyun Soon Lillehoj, Sungwon Kim, Eun Jung Sohn, Ki Duk Song, Jae Yong Han (2001). Generation and characterization of recombinant scFv antibodies detecting Eimeria acervulina surface antigens. Hybridoma. June, 20(3), 175-181.
• Ki Duk Song, Jae Yong Han, Wongi Min, Hyun S. Lillehoj, Sung Won Kim, Jin-Kyoo Kim (2001). Molecular cloning and characterization of cDNA encoding immunoglobulin heavy and light chain variable regions from four chicken monoclonal antibodies specific to surface antigens of intestinal parasites, Eimeria acervulina. The Journal of Microbiology. March, 39(1), 49-55.
• Cheol H. Yun, Hyun S. Lillehoj, Jingtao Zhu, Wongi Min (2000). Kinetic differences in intestinal and systemic interferon-γand antigen-specific antibodies in chickens experimentally infected with Eimeria maxima. Avian Diseases. April-June, 44(2), 305-312.
• Wongi Min, Hee-Jong Woo, Chul-Sang Lee, Kyung-kwang Lee, Won Kee Yoon, Hyoung Woo Park, Myoung Hee Kim (1998). 307-bp fragment in HOXA7 upstream sequence is sufficient for anterior boundary formation. DNA and Cell Biology. 17(3), 293-299.
• Myungsun Cho, Chuog Shin, Wongi Min, Myoung Hee Kim (1997). Rapid analysis for the isolation of novel genes encoding putative effectors to the position-specific regulatory element of murine Hoxa-7. Mol. Cells. 7(2), 220-225.
• Wongi Min, Myungsun Cho, Seung Ik Jang, Hwa-Hyoung Chang, Chul-Sang Lee, Moo-hyung Jun, Myoung Hee Kim (1996). Sequence and functional analysis of an upstream regulatory region of human HOXA7 gene. Gene. 182(1-2), 1-6.
• Wongi Min, Jong Hoon Park, Wook Joon Chung, Ho-Yong Park, Myoung Hee Kim (1995). Position-specific control element of murine Hoxa-7 is conserved among several species. Korean J. Genetics. 17(2), 123-132.
• Seung-ik Jang, Wongi Min, Jong-hoon Park, Chul-sang Lee, Kyung-kwang Lee, Young-won Lee, Moo-hyung Jun, Myoung Hee Kim (1995). Analysis of human HOXA gene control region and its effects on anterior-posterior axial pattern formation using transgenic mouse embryo. Korean J. Vet. Res. 35(1), 95-105.
• Jong Hoon Park, Wongi Min, Hwa-Hyoung Chang, Myoung Hee Kim (1995). Isolation of 961E5 yeast artificial chromosome DNA clone containing the plausible human HOXA cluster. Korean J. Biochem. 27(1), 25-31.
• Wongi Min, Moo-hyung Jun, Jung-bok Lee, Byoung-han Kim, Soo-hwan An (1989). Restriction endonuclease analysis of infectious bovine rhinotracheitis virus isolated in Korea. J. of Kor. Soc. of Virology. 19(1), 1-10.
• Seong-kuk Park, Moo-hyung Jun, Hun-jun Lee, Wongi Min (1989). Detection of blocking factors in the serum from the guinea pigs sensitized with Mycobacterium spp. by using leukocyte adherence inhibition test. Korean J. Vet. Publ. Hith. 13(1), 71-78.
• Seong-kuk Park, Moo-hyung Jun, Hun-jun Lee, Wongi Min, Yong-dhuk Yoon (1989). Specificity of cell-mediated immunity in guinea pigs sensitized with Mycobacterium spp. using the leukocyte adherence inhibition test. Korean J. Vet. Res. 29(3), 283-289.
• Moo-hyung Jun, Duck-hwan Kim, Soo-hwan An, Jung-bok Lee, Wongi Min (1989). Application of monoclonal antibody to develop diagnostic techniques for infectious bovine rhinotracheitis virus. II. Diagnosis of infectious bovine rhinotracheitis by using monoclonal antibody. Korean J. Vet. Res. 29(1), 27-35.
• Wongi Min, Moo-hyung Jun, Seong-Kuk Park, Soo-hwan An, Yeon-ho Cha (1988). Experimental infection of infectious bovine rhinotracheitis virus to rabbits immunosuppressed with Dexamethasone. Korean J. Vet. Res. 28(1), 105-110.

학력 사항

• 2011-2014 : Ph.D., Veterinary Microbiology and Immunology College of Veterinary Medicine, Gyeongsang National University Dissertation: Comparative immune responses of ducks and chickens infected with Riemerella anatipestifer.
• 2008-2010 : M.S., Veterinary Microbiology and Immunology College of Veterinary Medicine, Gyeongsang National University Dissertation: Cross-immunity of Korean isolates of Eimeria maxima.
• 2002-2008 : B.S., D.V.M College of Veterinary Medicine, Gyeongsang National University

주요경력

• Apr, 2008- Apr, 2011 Public Quarantine Veterinarian (alternative military service) National Advanced Livestock Laboratory, Gyeongsangnam-do
• Mar, 2014- Jan, 2015 Post-Doctoral Associate College of Veterinary Medicine and Institute of Animal Medicine, Gyeongsang National University
• Feb, 2015- present Post-Doctoral fellow Animal Bioscience and Biotechnology Laboratory, Agricultural Research Service, U.S. Department of Agriculture

연구내용

• 조류의 전염성 질병에서의 숙주 방어면역 연구
• 조류의 소화기성 질병에 있어서 세포성 면역 유전자 탐색 및 기능 분석 연구
• 조류의 면역반응 연구를 위한 면역분자들의 항체 개발
• 조류의 항생제 대체제 개발 시스템 구축을 위한 생체외 모델 개발
• 숙주의 면역조절을 통한 전염병 예방 연구

주요연구업적(논문 등)

• Cammayo, P.L.T., Fernandez-Colorado, C.P., Flores, R.A., Roy, A., Kim, S., Lillehoj, H.S., Kim, W.H. & Min, W. “IL-17A treatment influences murine susceptibility to experimental Riemerella anatipestifer infection.” Developmental and Comparative Immunology, 2020, Vol. 106, pp. 103633
• Chaudhari, A.A., Kim, W.H. & Lillehoj, H.S. “Development and characterization of monoclonal antibodies specific for chicken interleukin-13 and their neutralizing effects in chicken primary monocytes.”, Poultry Science, 2020, Vol. 99, pp. 772-782.
• Book; Coccidiosis in Livestock, Poultry, Companion Animals and Humans. 1st edition. Published by CRC Press (2019).
• Kim, W.H., Chaudhari, A.A. & Lillehoj, H.S. “Involvement of T Cell Immunity in Avian Coccidiosis.” Frontiers in Immunology, 2019, 10:2732.
• Flores, R.A., Fernandez-Colorado, C.P., Afrin, F., Cammayo, P.L.T., Kim, S., Kim, W.H. & Min, W. “Riemerella anatipestifer infection in ducks induces IL-17A production, but not IL-23p19.”, Scientific Reports, 2019, 9:13269.
• Kim, W.H., Lillehoj, H.S. & Min, W. “Indole Treatment Alleviates Intestinal Tissue Damage Induced by Chicken Coccidiosis Through Activation of the Aryl Hydrocarbon Receptor.”, Frontiers in Immunology, 2019, 10:560.
• Chaudhari, A.A., Kim, W.H. & Lillehoj, H.S. “Interleukin-4 (IL-4) may regulate alternative activation of macrophage-like cells in chickens: A sequential study using novel and specific neutralizing monoclonal antibodies against chicken IL-4.”, Veterinary Immunology and Immunopathology, 2018, Vol. 205, pp. 72-82.
• Lee, Y., Kim, W.H., Lee, S.J. & Lillehoj, H.S. “Detection of chicken interleukin-10 production in intestinal epithelial cells and necrotic enteritis induced by Clostridium perfringens using capture ELISA.”, 2018 Veterinary Immunology and Immunopathology, 2018, Vol. 204, pp. 52-58. (co-first author)
• Fernandez, C.P., Afrin, F., Flores, R.A., Kim, W.H., Jeong, J., Kim, S., Lillehoj, H.S. & Min, W. “Identification of duck IL-4 and its inhibitory effect on IL-17A expression in R. anatipestifer-stimulated splenic lymphocytes.”, Molecular Immunology, 2018, Vol. 95, pp. 20-29.
• de Leeuw, E.P., Lee, S.H., Kim, W.H., Kwasny, S.M., Opperman, T.J. & Lillehoj, H.S. “Pleiotropic Anti-Infective Effects of Defensin-Derived Antimicrobial Compounds.”, Avian Diseases, 2018, Vol. 62, pp. 381-387.
• Afrin, F., Fernandez, C.P., Flores, R.A., Kim, W.H., Jeong, J., Chang, H.H., Kim, S., Lillehoj, H.S. & Min, W. “Downregulation of common cytokine receptor γ chain inhibits inflammatory responses in macrophages stimulated with Riemerella anatipestifer”, Developmental and Comparative Immunology, 2017, Vol. 81, pp. 225-234.
• Fernandez, C.P., Afrin, F., Flores, R.A., Kim, W.H., Jeong, J., Kim, S., Chang, H.H., Lillehoj, H.S. & Min, W. “Downregulation of inflammatory cytokines by berberine attenuates Riemerella anatipestifer infection in ducks”, Developmental and Comparative Immunology, 2017, Vol. 77. pp. 121-127.
• Gadde, U., Kim, W. H., Oh, S.T. & Lillehoj, H. S. “Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review”, Animal Health Research Reviews, 2017, Vol. 9, pp. 1-20.
• Kim, W. H., Lillehoj, H. S. & Min, W. “Evaluation of the Immunomodulatory Activity of the Chicken NK-Lysin-Derived Peptide cNK-2” Scientific Reports, 2017, 7:45099.
• Kim, W. H., Lillehoj, H. S., Lim, Y., Min, W., Sullivan, Y. B., Kakach, L. & LaBresh, J.W. 2017 “Development and characterization of mouse monoclonal antibodies reactive with chicken CXCLi2”, Developmental and Comparative Immunology, 2017, Vol. 72, pp. 30-36.
• Fernandez, C. P., Kim, W. H., Diaz, J. A., Jeong, J., Afrin, F., Kim, S., Jang, H. K., Lee, B. H., Yim, D., Lillehoj, H. S. & Min, W. 2016, “Upregulation of duck interleukin-17A during Riemerella anatipestifer infection”, Developmental and Comparative Immunology, 2016, Vol. 63, pp. 36-46. (co-first author)
• Diaz, J. A., Kim, W. H., Fernandez, C. P., Jeong, J., Afrin, F., Lillehoj, H. S., Kim, S., Kim, S., Dalloul, R. A. & Min, W. 2016, “Identification and expression analysis of duck interleukin-17D in Riemerella anatipestifer infection”, Developmental and Comparative Immunology, 2016, Vol. 61, pp. 190-197. (co-first author)
• Kim, W. H., Lillehoj, H.S. & Gay, C.G. 2016, “Using genomics to identify novel antimicrobials”, Scientific and Technical Review (Revue scientifique et technique), vol 35, pp. 95-103.
• Kim, W. H., Fernandez, C. P., Diaz J. A., Jeong J., Kim S., Lillehoj, H. S., Chang H. H. & Min, W. 2015, “Molecular cloning, characterization and mRNA expression of duck interleukin-17F”, Veterinary immunology and immunopathology, Vol. 164, pp.194-200.
• Jeong, J., Kim, W.H., Fernandez, C.P., Kim, S., Kim, Y.H., Jang, H.K., Lillehoj, H.S., Woo, H.J. & Min, W. 2015, "Different strategies for producing naturally soluble form of common cytokine receptor gamma chain", Developmental and comparative immunology, vol. 48, no. 1, pp. 13-21.
• Jeong, J., Kim, W.H., Yeo, J., Fernandez, C.P., Kim, S., Lee, Y.J., Lillehoj, H.S. & Min, W. 2014, "Identification of alternatively spliced isoforms of interleukin-2/15 receptor beta chain in ducks", Veterinary immunology and immunopathology, vol. 162, no. 3-4, pp. 154-161. (co-first author)
• 6. Kim, W.H., Jeong, J., Park, A.R., Yim, D., Kim, S., Chang, H.H., Yang, S.H., Kim, D.H., Lillehoj, H.S. & Min, W. 2014, "Downregulation of chicken interleukin-17 receptor A during Eimeria infection", Infection and immunity, vol. 82, no. 9, pp. 3845-3854.
• 5. Min, W., Kim, W.H., Lillehoj, E.P. & Lillehoj, H.S. 2013, "Recent progress in host immunity to avian coccidiosis: IL-17 family cytokines as sentinels of the intestinal mucosa", Developmental and comparative immunology, vol. 41, no. 3, pp. 418-428.
• 4. Kim, W.H., Jeong, J., Park, A.R., Yim, D., Kim, Y.H., Kim, K.D., Chang, H.H., Lillehoj, H.S., Lee, B.H. & Min, W. 2012, "Chicken IL-17F: identification and comparative expression analysis in Eimeria-infected chickens", Developmental and comparative immunology, vol. 38, no. 3, pp. 401-409.
• 3. Jeong, J., Kim, W.H., Yoo, J., Lee, C., Kim, S., Cho, J.H., Jang, H.K., Kim, D.W., Lillehoj, H.S. & Min, W. 2012, "Identification and comparative expression analysis of interleukin 2/15 receptor beta chain in chickens infected with E. tenella", PloS one, vol. 7, no. 5, pp. e37704.
• 2. Yoo, J., Kang, S.H., Jeong, J., Kim, W.H., Kim, S., Lillehoj, H.S. & Min, W. 2011, "Effects of simple and disposable chicken cages for experimental Eimeria infections", The Korean journal of parasitology, vol. 49, no. 3, pp. 299-302
• 1. Lee, B.H., Kim, W.H., Jeong, J., Yoo, J., Kwon, Y.K., Jung, B.Y., Kwon, J.H., Lillehoj, H.S. & Min, W. 2010, "Prevalence and cross-immunity of Eimeria species on Korean chicken farms", The Journal of veterinary medical science/the Japanese Society of Veterinary Science, vol. 72, no. 8, pp. 985-989