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수의병리학실험실

홈으로 이동 교수진/실험실실험실 소개수의병리학실험실

과목 및 실험실 소개

병리학은 질병의 이치를 공부하는 학문으로서, 질병의 본질과 원인을 탐구하고 질병의 경과에 따른 세포의 형태 및 기능적 변화를 연구하여 질병 진단기술을 익히도록 하며, 나아가 질병의 치료 및 예방을 할 수 있도록 하는 것을 목표로 한다.

수의병리학은 기초와 임상과목을 연결해주는 교량 역할을 하는 학문으로, 본 연구실은 반려동물 및 산업동물에서 발생하는 다양한 질병 및 종양에 대한 정확한 진단을 제공함으로써 임상의학에 기여하고 있다. 또한 세포 및 분자수준에서의 병인론 규명을 통한 질병 발생 기전을 연구함으로써 생명과학 발전에 이바지 하고자 한다.

연구내용

  • 노화 및 손상 간세포 재생 촉진 기술 개발
  • 줄기세포를 이용한 조직 치료 기술 개발
  • 퇴행성 및 류마티스 관절염 치료기술 개발
  • 질병 조직 및 종양 진단 기술 개발

교수님소개

  • 홍일화 부교수
    홍일화 교수
    • 055-772-2365
    • 담당과목 수의병리학

학력 사항

  • 경북대학교 수의학과 (수의학사)
  • 경북대학교 대학원 수의학과 수의병리학 전공 (수의석사)
  • 경북대학교 대학원 수의학과 수의병리학 전공 (수의박사)

경력 사항

  • Huffington Center on Aging, Baylor College of Medicine, Houston, TX, USA (박사 후 연구원)
  • University of California-Berkeley, Berkeley, CA, USA (박사 후 연구원)

주요 연구업적(논문 등)

  • Kong JY, Yeon SC, Lee HJ, Kang C, Park JK, Jeong KS, Hong IH. Protective Effects of Nutria Bile against Thioacetamide-Induced Liver Injury in Mice.Evidence Based complementary Alternative medicine. 2019 Jun 25;2019:6059317
  • Yang HR, Lee H, Kim JH, Hong IH, Hwang DH, Rho IR, Kim GS, Kim E, Kang C. Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells. Nutrients. 2019 Mar 7;11(3). pii: E573
  • Gang DG, Sim CH, Lee TJ, Kong JY, Hong IH. Sebaceous cell differentiation in a canine oral papilloma. Journal of Veterinary Diagnostic Investigation. 2018 Jul;30(4):569-571
  • Kim HS, Kong JY, Kim JH, Yeon SC, Hong IH. A Case of Fascioliasis in A Wild Nutria, Myocastor coypus, in Republic of Korea. Korean Journal of Parasitology. 2018 Aug;56(4):375-378
  • Kim T, Kim JU, Yang K, Nam K, Choe D, Kim E, Hong IH, Lee H, Park J, Roh YH. Nanoparticle-patterned multicompartmental chitosan Capsule for oral delivery of oligonucleotides. ACS Biomatereials Science & Engineering. 2018 Dec, 4:4163-4173
  • Arayan LT, Kim HB, Bernardo Reyes AW, Xuan Huy NT, Hong IH, Lee K, Yeom JH, Park Y, Kim S. The immunomodulatory effect of antimicrobial peptide HPA3P restricts Brucella abortus 544 infection in BALB/c mice. Veterinary Microbiology. 2018 Nov;225:17-24.
  • Jeong DH, Ullah HMA, Goo MJ, Ghim SG, Hong IH, Kim AY, Jeon SM, Choi MS, Elfadl AK, Chung MJ, Lee EJ, Kim YD, Kim JH, Kim SY, Jeong KS. Effects of oral glucosamine hydrochloride and mucopolysaccharide protein in a rabbit model of osteoarthritis.International Journal of Rheumatic Diseases. 2018 Mar;21(3):620-628.
  • Kong JY, Kim HK, Lee HJ, Yeon SC, Park JK, Jeong KS, Hong IH. Embryonal rhabdomyosarcoma in a Siberian chipmunk (Tamias sibiricus): a case report. Veterinarni Medicina 2017:62(9) 527-531.
  • Hong IH, Choi JY, Kim AY, Lee EM, Kim JH, Park JH, Choi SW, Jeong KS. Anti-rheumatoid arthritic effect of fermented adlay and achyranthes japonica nakai on collagen-induced arthritis in mice. Food and Agricultural Immunology 2017;28(1): 14-26.
  • Viscarra JA, Wang Y, Hong IH, Sul HS. Transcriptional activation of lipogenesis by insulin requires phosphorylation of MED17 by CK2. Science Signaling. 2017 Feb 21;10(467).596.
  • Song Y, Kim HD, Lee MK, Hong IH, Won CK, Bai HW, Lee SS, Lee S, Chung BY, Cho JH. Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model. PLoS One. 2017 Jan 10;12(1):e0169509.
  • Hong IH, Kang SY, Kim JH, Seok SH, Lee SK, Hong SJ, Lee SY, Park SJ, Kong JY, Yeon SC. Histopathological findings in wild Nutrias (Myocastor coypus) with Capillaria hepatica infection.Journal of Veterinary Medical Science. 2016 Jan 10;78(12):1887-1891.
  • Jin J, Hong IH, Lewis K, Iakova P, Breaux M, Jiang Y, Sullivan E, Jawanmardi N, Timchenko L, Timchenko NA.Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration.Hepatology. 2015 Jan;61(1):315-25. (Co-first author)
  • Hong IH, Lewis K, Iakova P, Jin J, Sullivan E, Jawanmardi N, Timchenko L, Timchenko N. Age-associated Change of C/EBP Family Proteins Causes Severe Liver Injury and Acceleration of Liver Proliferation after CCl4Treatments.TheJournal of Biological Chemistry. 2014 Jan 10;289(2):1106-18.
  • Hong IH, Park SJ, Goo MJ, Lee HR, Park JK, Ki MR, Kim SH, Lee EM, Kim AY, Jeong KS. JNK1 and JNK2 regulate α-SMA in hepatic stellate cells during CCl4-inducedfibrosisintheratliver.Pathology International. 2013 Oct;63(10):483-91. (Journal cover page)
  • Hong IH, Han SY, Ki MR, Moon YM, Park JK, You SY, Lee EM, Kim AY, Lee EJ, Jeong JH, Kang KS, Jeong KS. Inhibition of Kupffer Cell Activity Improves Transplantation of Human Adipose-derived Stem Cells and Liver Functions. Cell Transplantation. 2013 Mar;22(3):447-59.
  • Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M, Moore D, Timchenko NA. FXR inhibits gankyrin in mouse livers and prevents development of liver cancer. Hepatology 2013 Mar;57(3):1098-106
  • Hong IH, Goo MJ, Han SY, Ki MR, Park JK, Hong KS, Hwang OK, Kim TH, Yoo SE, Jeong KS. Ascorbic acid deficiency accelerates aging of hepatic stellate cells with up-regulation of PPARγ. Histology and Histopathology. 2012 Feb;27(2):171-9.
  • Hong IH, Jeong YW, Shin T, Hyun SH, Park JK, KI MR, Han SY, Park SI, Lee JH, Lee EM, Kim AY, You SY, Hwang WS, Jeong KS. Morphological abnormalities, impaired fetal development and decrease in myostatin expression following somatic cell nuclear transfer in dogs. Molecular Reproduction & Development. 2011 May;78(5):337-46.
  • Hong IH, Ji H, Hwa SY, Jeong WI, Jeong DH, Do SH, Kim JM, Ki MR, Park JK, Goo MJ, Hwang OK, Hong KS, Han JY, Chung HY, Jeong KS.The protective effect of ENA Actimineral resource A on CCl4-induced liver injury in rats. Marine Biotechnology (NY).2011Jun;13(3):462-73.
  • Hong IH, Bae SH, Lee SG, Park JK, Ji AR, Ki MR, Han SY, Lee EM, Kim AY, You SY, Kim TH, Jeong KS. Mucosa-associated lymphoid tissue lymphoma of the third eyelid conjunctiva in a dog. Veterinary Ophthalmology. 2011 Jan;14(1):61-5.
  • Hong IH, Kwon TE, Lee SK, Park JK, Ki MR, Park SI, Jeong KS. Fetal death of dogs after the ingestion of a soil conditioner. Experimental Toxicologic Pathology. 2011 Jan;63(1-2):113-7.
  • Ki MR, Lee HR, Park JK, Hong IH, Han SY, You SY, Lee EM, Kim AY, Lee SS, Jeong KS. Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation. Journal of Nutritional Biochemisty. 2011 Jun;22(6):535-42.
  • Park JK, Ki MR, Lee HR, Hong IH, Ji AR, Ishigami A, Park SI, Kim JM, Chung HY, Yoo SE, Jeong KS. VitaminC deficiency attenuates liver fibrosis by way of up-regulated peroxisome proliferator-activated receptor-gamma expression in senescence marker protein30 knockout mice. Hepatology. 2010 May;51(5):1766-77.
  • Hong IH, Lee HS, Park JK, Goo MJ, Yuan DW, Hwang OK, Hong KS, Han JY, JI AR, Ki MR,Jeong KS. Actinomycosis in a pet rabbit. Journal of Veterinary Dentistry. 2009 Summer;26(2):110-1.
최근 업데이트 일시 : 2023/03/07 11:22:46